GRIN lens systems for medical applications

Brain Imaging – one of the most enabling applications of GRINTECH micro-optics

 Endomicroscopy using GRINTECH lenses and assemblies allows an in-vivo imaging access to deep tissue regions in the brain, especially in non-humans. It helps to understand disease formation and progression on a cellular level of the tissue.

To support our customers even better by providing appropriate biological techniques and protocols, GRINTECH has created a partnership with Inscopix Inc. in Palo Alto, California, one of the leading technology providers in neuroscience microscopic imaging.

Beginning on December 1st, 2015 Inscopix will distribute exclusively our products in the field of non-confocal, single photon epi-fluorescence imaging for neuroscience applications in non-humans (see also our declaration).

  • developed for deep tissue imaging (epifluorescence)
  • offered as GRIN Singlets with NA 0.5 on both sides
  • offered as GRIN Doublets with object side NA of 0.5 and image side NA of 0.19
  • GRIN-Systems offered with different lengths

Brain Imaging – one of the most enabling applications of GRINTECH micro-optics

 Endomicroscopy using GRINTECH lenses and assemblies allows an in-vivo imaging access to deep tissue regions in the brain, especially in non-humans. It helps to understand disease formation and progression on a cellular level of the tissue.

To support our customers even better by providing appropriate biological techniques and protocols, GRINTECH has created a partnership with Inscopix Inc. in Palo Alto, California, one of the leading technology providers in neuroscience microscopic imaging.

Beginning on December 1st, 2015 Inscopix will distribute exclusively our products in the field of non-confocal, single photon epi-fluorescence imaging for neuroscience applications in non-humans (see also our declaration).

  • developed for deep tissue imaging (Multi-Photon Microscopy)
  • offered as GRIN Singlets with NA 0.5 on both sides
  • offered as GRIN Doublets with object side NA of 0.5 and image side NA of 0.19
  • GRIN-Systems offered with different lengths

Objectives for Fluorescence-Mikroscopy:

  • numerical aperture - object = 0.80 / 0.80
  • numerical aperture - imaged = 0.18 / 0.415
  • magnification 4.65x / 1.92x
  • recommended excitation wavelength 488 nm
  • mounted in stainless steel holder

 

Objectives for 2-Photon-Mikroscopy:

  • numerical aperture - object = 0.80 / 0.80
  • numerical aperture - imaged = 0.18 / 0.415
  • magnification 4.8x / 1.92x
  • recommended excitation wavelength 800 - 900 nm
  • mounted in stainless steel holder

Objectives for Fluorescence-Mikroscopy:

  • numerical aperture - object = 0.8 / 0.8
  • numerical aperture - image = 0.18 / 0.5
  • magnification 4.65x / 1.70x
  • recommended excitation wavelength 488 nm
  • mounted in stainless steel

Objectives for 2-Photon-Mikroscopy:

  • numerical aperture - object = 0.8 
  • numerical aperture - image = 0.18
  • magnification 4.76x
  • recommended excitation wavelength 800 - 900 nm
  • mounted in stainless steel
  • compared to the previous versions with significantly increase of the usable field of view and broader chromatic correction
  • higher confocal sensitivity
  • numerical aperture - object = 0.70 - 0.75
  • numerical aperture - image = 0.32 / 0.16 
  • magnification 2.2x - 2.3x / 4.5 x
  • mounted in stainless steel

 

 

  • xyz-stage and objective mounting to connect and align our GRIN-Microsystems to microscope objectives
  • for microscope objective diameter 30 mm (standard), for smaller diameters optional adapter rings are available
  • adjestment travel: : x: 7.5 mm, y: 6.5 mm, z: 6.5 mm
  • easy pich and drop of the jawls with magnetic pull